Biomecánica

Portada

2023-12-21T21:43:23+00:00

Portada V30

Datos de la revista, Consejo de Redacción y Normas editoriales

2023-12-21T21:48:00+00:00

Datos de la revista, Consejo de Redacción y Normas editoriales

Índice

2023-12-21T21:49:56+00:00

Índice V30

Norbornene-chitosan spray-dried microspheres for peptide conjugation using thiol-ene “photoclick” chemistry

2023-07-20T13:53:29+00:00

The action of bioactive peptides, such as antimicrobial peptides (AMP), in the human body is often compromised by limited residence time and stability in the target site. Bioconjugation of peptides to biomaterial surfaces is one of the strategies that may overcome these limitations. Herein, norbornene-chitosan (NorChit) microspheres were engineered to react with thiolated peptides by thiol-ene “photoclick” chemistry. NorChit microspheres were produced by spray drying and crosslinked with dithiothreitol (DTT) to prevent their solubilization. Microspheres with a diameter of 5 ± 2 µm showed round and smooth morphology with pockets over the surface that could be related with hydrophobic interactions between internal norbornene groups. Thiol-ene bioconjugation carried out using a fluorescent model peptide, showed a yield of 45%, whereas using the peptide but without UV exposure indicated a maximum of peptide adsorption of 30%. Altogether, NorChit microspheres show the potential for carrying bioactive peptides, which may open avenues for AMP activity onto harsh environments in the body.

Asymmetry in force production between unilateral and bilateral standing broad jumps in young senior amateur basketball players

2023-07-18T11:28:07+00:00

The main aim of this study was to assess the between-session reliability of performance and asymmetry variables between unilateral and bilateral standing broad jumps (SBJ). Twenty-four amateur basketball players completed two identical sessions which consisted of four unilateral SBJs (two with each leg) and two bilateral SBJs. Mean and peak values of force, velocity and power, and impulse were obtained separately for each leg using a dual force platform. Inter-limb asymmetries were computed using the standard percentage difference for the unilateral SBJ, and the bilateral asymmetry index-1 for the bilateral SBJ. All performance variables generally presented an acceptable absolute reliability for both SBJs with some exceptions for mean force, mean power, and peak power obtained with both legs. Asymmetry variables always showed unacceptable reliability and slight to fair levels of agreement in their direction except for unilateral SBJ peak velocity and bilateral SBJ peak power that showed moderate agreement for both SBJs. These results highlight that single-leg performance variables can be generally obtained with acceptable reliability regardless of the SBJ variant, but the reliability of the inter-limb asymmetries in the conditions examined in the present study is unacceptable to track individual changes in ground reaction force production.

Congreso 2024

2023-12-21T21:51:38+00:00

Congreso 2024